Protein Modification Reagents
ACROBiosystems TEV Protease (active enzyme, HPLC verified) 1000U
TEV Protease is a recombinant form of Tobacco Etch Virus protease expressed in Escherichia coli. This protease is used to cleave affinity tags from fusion proteins. The TEV Protease recognition sequence with the highest catalytic efficiency is ENLYFQS/G, the cleavage site is between Q and S/G. TEV protease contains N-terminus His-tag, it can be removed by Ni2+ affinity resin for purification of the target protein.
eMolecules N-(hydroxy-PEG2)-N'-(propargyl-PEG4)-Cy5 | 2107273-06-1 | | 10mg
Broadpharm | N-(hydroxy-PEG2)-N'-(propargyl-PEG4)-Cy5 | 10mg | 298819370 | BP-23000 | 97.000 | 2107273-06-1 | | 737.380 | C42H57ClN2O7
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Medchemexpress LLC Tco-peg8-nhs ester | 2353409-95-5 | 95.0% | C32H54N2O14 | 10MG
TCO-PEG8-NHS ester is a PEG-based PROTAC linker with an N-hydroxysuccinimide (NHS) activated ester that enables efficient conjugation to primary amines. The molecule incorporates a trans-cyclooctene (TCO) moiety separated by an eight-unit PEG spacer to provide aqueous solubility and flexible spacing for bioconjugation and targeted protein degradation construct synthesis.
- NHS-activated ester for efficient amide bond formation.
- Eight-unit PEG spacer improves solubility and flexibility.
- Provides a trans-cyclooctene (TCO) handle for click chemistry.
- High reported purity (95.0%).
- Supplied in small-mass packages suitable for research use.
Medchemexpress LLC Folic acid-PEG5-Mal | 00-00-0 | 99.5% | C35H45N9O12 | 10MG
FA-PEG5-Mal is a polyethylene glycol (PEG)-based linker developed for constructing proteolysis-targeting chimeras (PROTACs). It combines a folic acid-derived ligand with a PEG5 spacer and a maleimide functional group to enable selective conjugation to thiol-containing partners. Supplied as a solid for laboratory research use, it offers high purity and convenient solubility in DMSO for bioconjugation and linker assembly workflows.
- Provides a folic acid ligand for target engagement
- Contains a PEG5 spacer to give flexible linker length
- Includes a maleimide functional handle for thiol coupling
- Supplied as a solid suitable for laboratory research use
- High purity for reliable synthetic results
- Soluble in DMSO (100 mg/mL) with ultrasonic assistance recommended
eMolecules N-(m-PEG4)-N'-(amino-PEG3)-Cy5, TFA salt | 2107272-96-6 | | 10mg
Broadpharm | N-(m-PEG4)-N'-(amino-PEG3)-Cy5, TFA salt | 10mg | 298819349 | BP-23008 | 97.000 | 2107272-96-6 | | 870.450 | C44H63ClF3N3O9
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Medchemexpress LLC N3-PEG11-CH2CH2Br | 2098982-00-2 | MFCD32696701 | >98.0% | 634.56 g/mol | C24H48BrN3O11 | 25 MG
N3-PEG11-CH2CH2Br is a bifunctional PEG11 linker bearing an azide and a terminal bromoethyl group. The hydrophilic PEG11 spacer provides aqueous solubility and flexibility, allowing the molecule to serve as a versatile building block for bioconjugation and probe/linker synthesis in biochemical assays and research workflows.
Medchemexpress LLC Hs-peg-sh (mw 3400) | 97.0% | 25 MG
HS-PEG-SH (MW 3400) is a linear homobifunctional PEG and a cross-linker, useful for drug delivery and the preparation of PEG hydrogels. It has a molecular weight of 3400 (Average) and appears as a white to light yellow solid. This product is for research use only.
- Linear homobifunctional PEG
- Cross-linker
- Utilized for drug delivery
- Used in the preparation of PEG hydrogels
- White to light yellow solid appearance
- Research use only
Medchemexpress LLC Biotin-PEG1-NH2 | 811442-85-0 | 97.0% | 330.45 | C14H26N4O3S | 25 MG
Biotin-PEG1-NH2 is a cleavable, biotinylated one-unit polyethylene glycol (PEG1) linker with a terminal amine used for antibody-drug conjugate (ADC) synthesis and general bioconjugation research. It supplies a short hydrophilic spacer bearing a biotin affinity tag for capture or detection and a primary amine for coupling to payloads.
- Cleavable 1-unit PEG linker.
- Terminal primary amine for conjugation.
- Biotin tag for affinity capture and detection.
- Molecular weight 330.45 g·mol⁻¹.
- Purity 97.0%.
- Supplied as a white to off-white solid.
- Available in 25 MG and larger package sizes.
- Store at 4°C and protect from light; in solvent, -80°C for up to 6 months, -20°C for up to 1 month.